Encuentra terminos de la Human Phenotype Ontology a partir de una palabra
o frase, en espanol (para los signos mas frecuentes en inmunodeficiencias)
o en ingles (todos los terminos y sus sinonimos). Sirve para armar el
fenotipo de iei_priorizar() o iei_buscar_fenotipo().
Value
Un tibble con hpo_id, termino, genes_panel (cuantos genes del
panel lo tienen anotado) e ic (contenido de informacion: mas alto es mas
especifico).
Examples
iei_buscar_hpo("neumonia")
#> # A tibble: 15 × 4
#> hpo_id termino genes_panel ic
#> <chr> <chr> <int> <dbl>
#> 1 HP:0006532 Recurrent pneumonia 83 3.49
#> 2 HP:0002090 Pneumonia 68 2.72
#> 3 HP:0020102 Pneumocystis jirovecii pneumonia 12 6.09
#> 4 HP:0006538 Recurrent bronchopulmonary infections 10 5.74
#> 5 HP:0031950 Usual interstitial pneumonia 6 5.86
#> 6 HP:0002100 Recurrent aspiration pneumonia 4 5.04
#> 7 HP:0005366 Recurrent streptococcus pneumoniae infections 4 7.18
#> 8 HP:0011949 Acute infectious pneumonia 3 6.78
#> 9 HP:0006527 Lymphocytic interstitial pneumonia 3 7.18
#> 10 HP:0011945 Bronchiolitis obliterans organizing pneumonia 2 7.88
#> 11 HP:0011951 Aspiration pneumonia 1 3.9
#> 12 HP:0033670 Organizing pneumonia 1 8.57
#> 13 HP:0033214 Recurrent viral pneumonia 1 8.57
#> 14 HP:5210428 HSV pneumonia 0 8.57
#> 15 HP:5210302 VZV pneumonitis 0 8.57
iei_buscar_hpo("candidiasis")
#> # A tibble: 15 × 4
#> hpo_id termino genes_panel ic
#> <chr> <chr> <int> <dbl>
#> 1 HP:0002728 Recurrent mucocutaneous candidiasis 28 4.49
#> 2 HP:0009098 Recurrent oral thrush 36 4.96
#> 3 HP:0005401 Recurrent Candida infection 16 5.58
#> 4 HP:0012203 Unusual fungal nail infection 12 5.35
#> 5 HP:0033351 Candida esophagitis 5 6.96
#> 6 HP:0012204 Recurrent vulvovaginal candidiasis 2 7.47
#> 7 HP:0005411 Chronic intestinal candidiasis 1 8.57
#> 8 HP:0033768 Penile thrush 0 8.57
#> 9 HP:5210253 Severe oral thrush 0 8.57
#> 10 HP:5210167 Hepatic candidiasis 0 8.57
#> 11 HP:5210252 Unusual oral thrush 0 4.96
#> 12 HP:5210198 Fungal kidney abscess 0 8.57
#> 13 HP:5210241 Recurrent onychomycosis 0 8.57
#> 14 HP:6001283 Severe Candida infection 0 8.57
#> 15 HP:5210102 Unusual Candida infection 0 4.66